Info
| ID | 464 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 2} |
| Abbreviation | RuPhen |
| SMILES | Cc1ccc(C(C)C)cc1.[Cl-].c1cnc2c(c1)ccc1cccnc12 |
TUCAN
C22H22N2Ru/(1-28)(2-41)(3-27)(4-23)(5-23)(6-24)(7-23)(8-32)(9-42)(10-33)(11-26)(12-35)(13-31)(14-34)(15-24)(16-24)(17-25)(18-29)(19-30)(20-40)(21-25)(22-25)(23-37)(24-40)(25-40)(26-33)(26-41)(27-28)(27-37)(28-38)(29-30)(29-38)(30-37)(31-35)(31-42)(32-34)(32-36)(33-36)(34-39)(35-39)(36-43)(38-40)(39-44)(41-45)(42-46)(43-44)(43-45)(44-46)(45-47)(46-47)
Measurements (16)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A2780 | 11 | — | 10.1039/d1dt00808k | 2021 |
| HeLa | 12 | — | 10.1016/j.jinorgbio.2020.11109... | 2020 |
| MCF-7 | 14 | — | 10.1016/j.jinorgbio.2020.11109... | 2020 |
| A2780 | 23 | — | 10.1007/s00775-012-0917-9 | 2012 |
| MES-SA | 24 | — | 10.1039/d1dt00808k | 2021 |
| A549 | 65 | — | 10.1007/s00775-021-01873-9 | 2021 |
| B16-F10 | 71 | — | 10.1007/s00775-021-01873-9 | 2021 |
| MCF-7 | 75 | — | 10.1007/s00775-021-01873-9 | 2021 |
| U373 | 99 | — | 10.1007/s00775-021-01873-9 | 2021 |
| HEK293 | 1.3e+02 | — | 10.1016/j.jinorgbio.2020.11109... | 2020 |
| A549 | — | — | 10.1016/j.jinorgbio.2015.07.01... | 2015 |
| MDA-MB-231 | — | — | 10.1016/j.jinorgbio.2015.07.01... | 2015 |
| MCF-7 | — | — | 10.1016/j.jinorgbio.2015.07.01... | 2015 |
| L-929 | — | — | 10.1016/j.jinorgbio.2015.07.01... | 2015 |
| MES-SA/Dx5 | — | — | 10.1039/d1dt00808k | 2021 |
| A2780cisR | — | — | 10.1039/d1dt00808k | 2021 |
Source-assisted 2D generator
Builds the drawing from source ligand graphs and explicit donor metadata, then uses Metal2D only for layout. Publication output uses black bonds without arrows or colour highlighting; validated octahedral enantiomers are encoded directly with solid and hashed wedge bonds.
Loading source metadata…
The generated SVG will appear here. The legacy ligand image above stays visible for side-by-side review.