Info
| ID | 4611 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 2 |
| Donor atoms | {"N": 7} |
| Abbreviation | 1 |
| SMILES | c1ccc(-c2ccccn2)nc1.c1ccc(-c2ccccn2)nc1.c1ccc(Cn2c(-c3ccccn3)nc3ccccc32)cc1 |
TUCAN
C39H31N7Ru/(1-58)(2-62)(3-62)(4-59)(5-41)(6-32)(7-43)(8-44)(9-34)(10-45)(11-47)(12-33)(13-46)(14-40)(15-36)(16-60)(17-61)(18-35)(19-42)(20-57)(21-38)(22-39)(23-49)(24-51)(25-50)(26-53)(27-54)(28-48)(29-37)(30-55)(31-52)(32-41)(32-63)(33-34)(33-43)(34-58)(35-36)(35-59)(36-44)(37-42)(37-60)(38-39)(38-57)(39-50)(40-41)(40-46)(42-53)(43-64)(44-67)(45-47)(45-56)(46-65)(47-48)(48-51)(49-51)(49-56)(50-66)(52-55)(52-61)(53-68)(54-55)(54-69)(56-62)(57-72)(58-74)(59-75)(60-76)(61-77)(62-71)(63-65)(63-71)(64-67)(64-74)(65-73)(66-70)(66-72)(67-75)(68-69)(68-76)(69-77)(70-71)(70-73)(72-78)(73-78)(74-78)(75-78)(76-78)(77-78)
Measurements (2)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HeLa | 3.2e+02 | — | 10.1007/s11243-019-00341-3 | 2022 |
| Vero | 3.6e+02 | — | 10.1007/s11243-019-00341-3 | 2022 |
🧬 Cell Death Types (1)
Apoptosis
high
«Furthermore, gene expression studies on BAX and BCL-2 genes and FACS analysis confirmed apoptosis as the mode of cell death.»