Info
| ID | 453 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"O": 1} |
| Abbreviation | 7 |
| SMILES | Cc1ccc(C(C)C)cc1.O=C(/C=C(\[O-])C(F)(F)F)c1ccc(Cl)cc1.[Cl-] |
TUCAN
C20Cl2F3O2Ru/(1-14)(2-13)(3-13)(4-6)(4-15)(5-17)(5-18)(6-14)(7-11)(7-15)(8-9)(8-16)(9-20)(10-12)(10-16)(11-14)(12-20)(13-15)(16-17)(17-22)(18-19)(18-21)(19-23)(19-24)(19-25)(20-27)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MRC-5 | 26 | — | 10.3390/ph14060518 | 2021 |
| COLO-320 | 29 | — | 10.3390/ph14060518 | 2021 |
| COLO-205 | 52 | — | 10.3390/ph14060518 | 2021 |
🧬 Cell Death Types (1)
Apoptosis
high
«Complex 5 was also reported to be cytotoxic against a series of human cancer cells and induced caspase-dependent cell death in leukemia cells [17].»