Info
| ID | 4512 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 2 |
| Donor atoms | {"N": 6} |
| Abbreviation | Ru-1b |
| SMILES | c1ccc(-c2ccccn2)nc1.c1ccc(-c2ccccn2)nc1.c1ccncc1.c1ccncc1 |
TUCAN
C30H26N6Ru/(1-45)(2-49)(3-30)(4-46)(5-31)(6-35)(7-38)(8-36)(9-37)(10-42)(11-39)(12-47)(13-40)(14-48)(15-52)(16-28)(17-29)(18-33)(19-41)(20-27)(21-32)(22-34)(23-44)(24-43)(25-50)(26-51)(27-30)(27-31)(28-36)(28-53)(29-37)(29-54)(30-46)(31-47)(32-40)(32-41)(33-39)(33-55)(34-44)(34-56)(35-36)(35-45)(37-38)(38-49)(39-42)(40-48)(41-52)(42-50)(43-44)(43-51)(45-59)(46-57)(47-57)(48-58)(49-60)(50-61)(51-62)(52-58)(53-54)(53-59)(54-60)(55-56)(55-61)(56-62)(57-63)(58-63)(59-63)(60-63)(61-63)(62-63)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | 98 | — | 10.1039/c6cc04813g | 2016 |
| T47D | — | — | 10.1016/j.jinorgbio.2022.11193... | 2022 |
| H23 | — | — | 10.1016/j.jinorgbio.2022.11193... | 2022 |
| HL60 | — | — | 10.1039/c6cc04813g | 2016 |
🧬 Cell Death Types (1)
Apoptosis
high
«Furthermore, flow cytometry confirmed the mechanism of cell death for 2a occurs via apoptosis with no visible sign of necrosis.»