Info
| ID | 447 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"O": 1, "N": 1} |
| Abbreviation | 1 |
| SMILES | Cc1ccc(C(C)C)cc1.[Cl-].[O-]n1ccccc1=S |
TUCAN
C15ClNORuS/(1-13)(2-12)(3-13)(4-5)(4-12)(5-11)(6-7)(6-10)(7-14)(8-9)(8-12)(9-11)(10-15)(11-13)(14-16)(15-16)(15-18)(16-17)
Measurements (10)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MRC-5 | 2.2 | — | 10.3390/ph14060518 | 2021 |
| COLO-320 | 3.3 | — | 10.3390/ph14060518 | 2021 |
| A549 | 3.6 | — | 10.1002/chem.201903109 | 2019 |
| SK-OV-3 | 7.5 | — | 10.1002/chem.201903109 | 2019 |
| OE19 | 11 | — | 10.1002/chem.201903109 | 2019 |
| COLO-205 | 14 | — | 10.3390/ph14060518 | 2021 |
| HCT-116 | 14 | — | 10.1002/chem.201903109 | 2019 |
| PC-3 | 23 | — | 10.1002/chem.201903109 | 2019 |
| HepG2 | 24 | — | 10.1002/chem.201903109 | 2019 |
| SW626 | 28 | — | 10.1002/chem.201903109 | 2019 |
🧬 Cell Death Types (1)
Apoptosis
high
«Complex 5 was also reported to be cytotoxic against a series of human cancer cells and induced caspase-dependent cell death in leukemia cells [17].»