Info
| ID | 4419 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 2} |
| Abbreviation | 3 |
| SMILES | Cc1ccc(C(C)C)cc1.Cc1ccc(NC(=S)NC(=O)c2ccccc2)cc1.[Cl-].[Cl-] |
TUCAN
C25Cl2N2ORuS/(1-21)(2-18)(3-21)(4-19)(5-14)(5-19)(6-16)(6-19)(7-8)(7-10)(8-11)(9-15)(9-23)(10-12)(11-20)(12-20)(13-17)(13-23)(14-22)(15-18)(16-22)(17-18)(20-24)(21-22)(23-27)(24-26)(24-28)(25-26)(25-27)(25-29)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| IMR-32 | 10 | — | 10.1021/acsomega.9b00349 | 2019 |
| MCF-7 | 12 | — | 10.1021/acsomega.9b00349 | 2019 |
| COLO-205 | 12 | — | 10.1021/acsomega.9b00349 | 2019 |
| A549 | 15 | — | 10.1021/acsomega.9b00349 | 2019 |
🧬 Cell Death Types (1)
Apoptosis
high
«The cells treated with the complexes showed upregulated caspase-3 compared to the control, and it was found that ROS and MMP were dose-dependent on analysis. Also, bright-field microscopy and DAPI sta...»