Info
| ID | 4412 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 4} |
| Abbreviation | Ru2 |
| SMILES | CCCCOc1ccc(-c2nc3c4cccnc4c4ncccc4c3[nH]2)cc1.Cc1ccc(C(C)C)cc1.[Cl-] |
TUCAN
C33H34N4ORu/(1-51)(2-35)(3-39)(4-35)(5-35)(6-40)(7-58)(8-44)(9-42)(10-37)(11-36)(12-41)(13-37)(14-36)(15-37)(16-43)(17-59)(18-46)(19-36)(20-45)(21-52)(22-52)(23-38)(24-38)(25-51)(26-66)(27-47)(28-60)(29-49)(30-66)(31-50)(32-48)(33-38)(34-69)(35-58)(36-58)(37-53)(38-52)(39-40)(39-53)(40-55)(41-46)(41-55)(42-43)(42-67)(43-56)(44-45)(44-59)(45-54)(46-53)(47-50)(47-57)(48-49)(48-56)(49-67)(50-60)(51-52)(51-66)(54-61)(54-63)(55-58)(56-65)(57-62)(57-64)(59-68)(60-70)(61-64)(61-69)(62-63)(62-70)(63-68)(64-71)(65-69)(65-71)(66-72)(67-72)(70-73)(71-73)(72-73)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HeLa | 32 | — | 10.1021/acs.inorgchem.4c03975 | 2024 |
| A549 | 44 | — | 10.1021/acs.inorgchem.4c03975 | 2024 |
| BEAS-2B | 46 | — | 10.1021/acs.inorgchem.4c03975 | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«thereby leading to intrinsic apoptotic pathways»