Info
| ID | 4411 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 2 |
| Donor atoms | {"N": 4} |
| Abbreviation | Ru1 |
| SMILES | Cc1ccc(C(C)C)cc1.[Cl-].c1ccc([P+](CCCCOc2ccc(-c3nc4c5cccnc5c5ncccc5c4[nH]3)cc2)(c2ccccc2)c2ccccc2)cc1 |
TUCAN
C51H48N4OPRu/(1-94)(2-94)(3-73)(4-50)(5-50)(6-50)(7-51)(8-80)(9-54)(10-52)(11-55)(12-79)(13-79)(14-62)(15-63)(16-59)(17-65)(18-75)(19-67)(20-64)(21-68)(22-72)(23-87)(24-60)(25-53)(26-61)(27-88)(28-71)(29-69)(30-77)(31-70)(32-96)(33-96)(34-66)(35-76)(36-74)(37-80)(38-49)(39-51)(40-56)(41-57)(42-86)(43-49)(44-58)(45-78)(46-49)(47-51)(48-101)(49-81)(50-86)(51-86)(52-54)(52-55)(53-69)(53-87)(54-97)(55-59)(56-57)(56-81)(57-82)(58-78)(58-82)(59-62)(60-63)(60-65)(61-64)(61-65)(62-97)(63-98)(64-98)(66-70)(66-77)(67-68)(67-95)(68-84)(69-83)(70-99)(71-72)(71-95)(72-84)(73-75)(73-88)(74-76)(74-77)(75-85)(76-99)(78-81)(79-80)(79-94)(80-96)(82-86)(83-90)(83-92)(84-93)(85-89)(85-91)(87-100)(88-102)(89-90)(89-103)(90-101)(91-92)(91-102)(92-100)(93-101)(93-103)(94-104)(95-104)(96-105)(97-105)(98-105)(99-105)(102-106)(103-106)(104-106)(105-106)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | 6.2 | — | 10.1021/acs.inorgchem.4c03975 | 2024 |
| HeLa | 13 | — | 10.1021/acs.inorgchem.4c03975 | 2024 |
| BEAS-2B | 82 | — | 10.1021/acs.inorgchem.4c03975 | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«thereby leading to intrinsic apoptotic pathways»