Info
| ID | 4335 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 2 |
| Donor atoms | {"N": 6} |
| Abbreviation | 6e |
| SMILES | Cc1ccnc(-c2cc(CN3CCN(c4ccccc4)CC3)ccn2)c1.Cc1ccnc(-c2cc(CN3CCN(c4ccccc4)CC3)ccn2)c1.Cc1ccnc(-c2cc(CN3CCN(c4ccccc4)CC3)ccn2)c1 |
TUCAN
C66H72N12Ru/(1-116)(2-115)(3-115)(4-116)(5-82)(6-73)(7-120)(8-76)(9-118)(10-117)(11-73)(12-117)(13-120)(14-73)(15-77)(16-86)(17-109)(18-80)(19-118)(20-78)(21-119)(22-94)(23-74)(24-81)(25-121)(26-119)(27-125)(28-121)(29-122)(30-83)(31-74)(32-85)(33-111)(34-122)(35-97)(36-74)(37-75)(38-87)(39-88)(40-110)(41-95)(42-123)(43-125)(44-128)(45-123)(46-92)(47-79)(48-128)(49-126)(50-124)(51-129)(52-90)(53-89)(54-93)(55-101)(56-98)(57-84)(58-112)(59-100)(60-126)(61-96)(62-129)(63-127)(64-124)(65-127)(66-91)(67-75)(68-75)(69-99)(70-114)(71-102)(72-113)(73-103)(74-107)(75-108)(76-104)(76-130)(77-80)(77-82)(78-104)(78-109)(79-105)(79-131)(80-135)(81-82)(81-85)(83-87)(83-92)(84-106)(84-132)(85-135)(86-103)(86-133)(87-136)(88-93)(88-136)(89-98)(89-138)(90-107)(90-134)(91-102)(91-138)(92-93)(94-107)(94-111)(95-105)(95-110)(96-106)(96-114)(97-108)(97-112)(98-100)(99-108)(99-137)(100-102)(101-103)(101-113)(104-117)(105-121)(106-124)(109-145)(110-149)(111-146)(112-147)(113-148)(114-150)(115-116)(115-139)(116-140)(117-139)(118-120)(118-139)(119-122)(119-143)(120-140)(121-143)(122-141)(123-125)(123-141)(124-144)(125-143)(126-128)(126-142)(127-129)(127-142)(128-144)(129-144)(130-133)(130-145)(131-137)(131-149)(132-134)(132-150)(133-148)(134-146)(135-140)(136-141)(137-147)(138-142)(145-151)(146-151)(147-151)(148-151)(149-151)(150-151)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HT-29 | — | 5.9 | 10.1016/j.ejmech.2024.116909 | 2024 |
| A549 | — | 7.9 | 10.1016/j.ejmech.2024.116909 | 2024 |
| 4T1 | — | 10 | 10.1016/j.ejmech.2024.116909 | 2024 |
🧬 Cell Death Types (2)
Ferroptosis
high
«it induced ferroptosis and immunogenic cell death of A549 cells by regulating the expression of relevant markers.»
Immunogenic Cell Death
high
«it induced ferroptosis and immunogenic cell death of A549 cells by regulating the expression of relevant markers.»
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Builds the drawing from source ligand graphs and explicit donor metadata, then uses Metal2D only for layout. Publication output uses black bonds without arrows or colour highlighting; validated octahedral enantiomers are encoded directly with solid and hashed wedge bonds.
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