home← all complexes D-MPNN

Complex #4335 — Ru(2) [6e]

2D Structure

Structure
⬇ MOL V3000

Info

ID4335
MetalRu
Oxidation state2
Charge2
Donor atoms{"N": 6}
Abbreviation6e
SMILESCc1ccnc(-c2cc(CN3CCN(c4ccccc4)CC3)ccn2)c1.Cc1ccnc(-c2cc(CN3CCN(c4ccccc4)CC3)ccn2)c1.Cc1ccnc(-c2cc(CN3CCN(c4ccccc4)CC3)ccn2)c1

TUCAN

C66H72N12Ru/(1-116)(2-115)(3-115)(4-116)(5-82)(6-73)(7-120)(8-76)(9-118)(10-117)(11-73)(12-117)(13-120)(14-73)(15-77)(16-86)(17-109)(18-80)(19-118)(20-78)(21-119)(22-94)(23-74)(24-81)(25-121)(26-119)(27-125)(28-121)(29-122)(30-83)(31-74)(32-85)(33-111)(34-122)(35-97)(36-74)(37-75)(38-87)(39-88)(40-110)(41-95)(42-123)(43-125)(44-128)(45-123)(46-92)(47-79)(48-128)(49-126)(50-124)(51-129)(52-90)(53-89)(54-93)(55-101)(56-98)(57-84)(58-112)(59-100)(60-126)(61-96)(62-129)(63-127)(64-124)(65-127)(66-91)(67-75)(68-75)(69-99)(70-114)(71-102)(72-113)(73-103)(74-107)(75-108)(76-104)(76-130)(77-80)(77-82)(78-104)(78-109)(79-105)(79-131)(80-135)(81-82)(81-85)(83-87)(83-92)(84-106)(84-132)(85-135)(86-103)(86-133)(87-136)(88-93)(88-136)(89-98)(89-138)(90-107)(90-134)(91-102)(91-138)(92-93)(94-107)(94-111)(95-105)(95-110)(96-106)(96-114)(97-108)(97-112)(98-100)(99-108)(99-137)(100-102)(101-103)(101-113)(104-117)(105-121)(106-124)(109-145)(110-149)(111-146)(112-147)(113-148)(114-150)(115-116)(115-139)(116-140)(117-139)(118-120)(118-139)(119-122)(119-143)(120-140)(121-143)(122-141)(123-125)(123-141)(124-144)(125-143)(126-128)(126-142)(127-129)(127-142)(128-144)(129-144)(130-133)(130-145)(131-137)(131-149)(132-134)(132-150)(133-148)(134-146)(135-140)(136-141)(137-147)(138-142)(145-151)(146-151)(147-151)(148-151)(149-151)(150-151)

Measurements (3)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
HT-29—5.9 10.1016/j.ejmech.2024.116909 2024
A549—7.9 10.1016/j.ejmech.2024.116909 2024
4T1—10 10.1016/j.ejmech.2024.116909 2024

🧬 Cell Death Types (2)

Ferroptosis high
«it induced ferroptosis and immunogenic cell death of A549 cells by regulating the expression of relevant markers.»
Immunogenic Cell Death high
«it induced ferroptosis and immunogenic cell death of A549 cells by regulating the expression of relevant markers.»