Info
| ID | 4331 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 2 |
| Donor atoms | {"N": 6} |
| Abbreviation | 6a |
| SMILES | Cc1ccnc(-c2cc(CN3CCC(C)CC3)ccn2)c1.Cc1ccnc(-c2cc(CN3CCC(C)CC3)ccn2)c1.Cc1ccnc(-c2cc(CN3CCC(C)CC3)ccn2)c1 |
TUCAN
C54H69N9Ru/(1-112)(2-100)(3-109)(4-88)(5-71)(6-105)(7-112)(8-88)(9-103)(10-109)(11-81)(12-71)(13-78)(14-110)(15-110)(16-82)(17-70)(18-79)(19-111)(20-111)(21-89)(22-70)(23-76)(24-77)(25-89)(26-113)(27-113)(28-101)(29-80)(30-115)(31-71)(32-70)(33-114)(34-74)(35-72)(36-106)(37-90)(38-115)(39-74)(40-74)(41-90)(42-72)(43-83)(44-72)(45-73)(46-75)(47-104)(48-107)(49-91)(50-91)(51-114)(52-92)(53-116)(54-87)(55-73)(56-75)(57-117)(58-86)(59-73)(60-84)(61-92)(62-117)(63-102)(64-93)(65-108)(66-93)(67-116)(68-75)(69-85)(70-95)(71-100)(72-101)(73-102)(74-97)(75-98)(76-94)(76-118)(77-96)(77-119)(78-95)(78-121)(79-94)(79-105)(80-96)(80-106)(81-95)(81-103)(82-97)(82-104)(83-97)(83-122)(84-99)(84-108)(85-98)(85-107)(86-98)(86-123)(87-99)(87-120)(88-100)(88-109)(89-100)(89-110)(90-101)(90-111)(91-101)(91-113)(92-102)(92-114)(93-102)(93-116)(94-112)(96-115)(99-117)(103-127)(104-129)(105-128)(106-130)(107-132)(108-131)(109-124)(110-124)(111-125)(112-124)(113-125)(114-126)(115-125)(116-126)(117-126)(118-121)(118-128)(119-122)(119-130)(120-123)(120-131)(121-127)(122-129)(123-132)(127-133)(128-133)(129-133)(130-133)(131-133)(132-133)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| 4T1 | 85 | 11 | 10.1016/j.ejmech.2024.116909 | 2024 |
| HT-29 | — | 8 | 10.1016/j.ejmech.2024.116909 | 2024 |
| A549 | — | 9.4 | 10.1016/j.ejmech.2024.116909 | 2024 |
🧬 Cell Death Types (2)
Ferroptosis
high
«it induced ferroptosis and immunogenic cell death of A549 cells by regulating the expression of relevant markers.»
Immunogenic Cell Death
high
«it induced ferroptosis and immunogenic cell death of A549 cells by regulating the expression of relevant markers.»