Info
| ID | 4318 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"S": 1, "N": 3} |
| Abbreviation | RuBCAM |
| SMILES | [Cl-].[S-]/C(=N\N=C/C=C/c1ccccc1)N1CCOCC1.c1ccccc1 |
TUCAN
C20H22N3ORuS/(1-23)(2-24)(3-25)(4-26)(5-38)(6-38)(7-40)(8-40)(9-39)(10-41)(11-41)(12-27)(13-28)(14-33)(15-35)(16-37)(17-39)(18-29)(19-31)(20-32)(21-30)(22-34)(23-24)(23-25)(24-26)(25-27)(26-28)(27-28)(29-30)(29-36)(30-31)(31-34)(32-34)(32-36)(33-35)(33-36)(35-37)(37-45)(38-40)(38-43)(39-41)(39-43)(40-46)(41-46)(42-43)(42-44)(42-47)(44-45)(44-48)(45-48)(46-48)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MDA-MB-231 | 45 | — | 10.1021/acsabm.4c00689 | 2024 |
| MCF-7 | 58 | — | 10.1021/acsabm.4c00689 | 2024 |
| HeLa | 92 | — | 10.1021/acsabm.4c00689 | 2024 |
| MCF-10A | 96 | — | 10.1021/acsabm.4c00689 | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«The active complexes were found to trigger apoptosis, a vital cellular process crucial for evaluating their potential as anticancer agents utilizing staining assays and flow cytometry analysis.»