Info
| ID | 4317 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"S": 1, "N": 3} |
| Abbreviation | RuBCAP |
| SMILES | [Cl-].[S-]/C(=N\N=C/C=C/c1ccccc1)N1CCCC1.c1ccccc1 |
TUCAN
C20H22N3RuS/(1-23)(2-24)(3-25)(4-26)(5-40)(6-40)(7-36)(8-36)(9-37)(10-37)(11-27)(12-28)(13-29)(14-33)(15-35)(16-39)(17-41)(18-41)(19-30)(20-34)(21-31)(22-32)(23-24)(23-25)(24-26)(25-27)(26-28)(27-28)(29-30)(29-38)(30-31)(31-34)(32-34)(32-38)(33-35)(33-38)(35-39)(36-37)(36-40)(37-41)(39-45)(40-43)(41-43)(42-43)(42-44)(42-46)(44-45)(44-47)(45-47)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MCF-7 | 90 | — | 10.1021/acsabm.4c00689 | 2024 |
| HeLa | 90 | — | 10.1021/acsabm.4c00689 | 2024 |
| MDA-MB-231 | 90 | — | 10.1021/acsabm.4c00689 | 2024 |
| MCF-10A | — | — | 10.1021/acsabm.4c00689 | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«The active complexes were found to trigger apoptosis, a vital cellular process crucial for evaluating their potential as anticancer agents utilizing staining assays and flow cytometry analysis.»