Info
| ID | 4316 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"S": 1, "N": 3} |
| Abbreviation | RuPCAC |
| SMILES | Cc1ccc(C(C)C)cc1.[Cl-].[S-]/C(=N\N=C/C=C/c1ccccc1)Nc1ccccc1 |
TUCAN
C26H28N3RuS/(1-44)(2-41)(3-42)(4-30)(5-30)(6-30)(7-51)(8-32)(9-43)(10-35)(11-39)(12-45)(13-52)(14-46)(15-40)(16-33)(17-34)(18-37)(19-31)(20-31)(21-29)(22-29)(23-31)(24-38)(25-29)(26-36)(27-47)(28-55)(29-48)(30-51)(31-51)(32-35)(32-53)(33-34)(33-50)(34-52)(35-39)(36-37)(36-48)(37-49)(38-47)(38-49)(39-40)(40-43)(41-42)(41-46)(42-44)(43-53)(44-50)(45-46)(45-50)(47-48)(49-51)(52-57)(53-55)(54-55)(54-56)(54-58)(56-57)(56-59)(57-59)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MCF-7 | 30 | — | 10.1021/acsabm.4c00689 | 2024 |
| MDA-MB-231 | 36 | — | 10.1021/acsabm.4c00689 | 2024 |
| HeLa | 40 | — | 10.1021/acsabm.4c00689 | 2024 |
| MCF-10A | — | — | 10.1021/acsabm.4c00689 | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«The active complexes were found to trigger apoptosis, a vital cellular process crucial for evaluating their potential as anticancer agents utilizing staining assays and flow cytometry analysis.»