Info
| ID | 4315 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"S": 1, "N": 3} |
| Abbreviation | RuPCAM |
| SMILES | Cc1ccc(C(C)C)cc1.[Cl-].[S-]/C(=N\N=C/C=C/c1ccccc1)N1CCOCC1 |
TUCAN
C24H30N3ORuS/(1-44)(2-35)(3-40)(4-37)(5-32)(6-32)(7-32)(8-31)(9-50)(10-52)(11-52)(12-53)(13-42)(14-49)(15-34)(16-53)(17-36)(18-50)(19-51)(20-51)(21-41)(22-33)(23-33)(24-33)(25-48)(26-31)(27-31)(28-38)(29-43)(30-39)(31-46)(32-48)(33-48)(34-44)(34-45)(35-40)(35-45)(36-41)(36-45)(37-38)(37-46)(38-47)(39-43)(39-47)(40-42)(41-42)(43-46)(44-49)(47-48)(49-56)(50-52)(50-55)(51-53)(51-55)(52-58)(53-58)(54-55)(54-57)(54-59)(56-57)(56-60)(57-60)(58-60)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MCF-7 | 9.2 | — | 10.1021/acsabm.4c00689 | 2024 |
| MDA-MB-231 | 14 | — | 10.1021/acsabm.4c00689 | 2024 |
| HeLa | 37 | — | 10.1021/acsabm.4c00689 | 2024 |
| MCF-10A | 75 | — | 10.1021/acsabm.4c00689 | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«The active complexes were found to trigger apoptosis, a vital cellular process crucial for evaluating their potential as anticancer agents utilizing staining assays and flow cytometry analysis.»