Info
| ID | 4314 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"S": 1, "N": 3} |
| Abbreviation | RuPCAP |
| SMILES | Cc1ccc(C(C)C)cc1.[Cl-].[S-]/C(=N\N=C/C=C/c1ccccc1)N1CCCC1 |
TUCAN
C24H30N3RuS/(1-40)(2-51)(3-41)(4-35)(5-37)(6-32)(7-32)(8-31)(9-52)(10-45)(11-52)(12-45)(13-53)(14-44)(15-42)(16-46)(17-46)(18-36)(19-34)(20-53)(21-32)(22-33)(23-50)(24-31)(25-31)(26-38)(27-43)(28-39)(29-33)(30-33)(31-48)(32-50)(33-50)(34-44)(34-47)(35-40)(35-47)(36-41)(36-47)(37-38)(37-48)(38-49)(39-43)(39-49)(40-42)(41-42)(43-48)(44-51)(45-46)(45-52)(46-53)(49-50)(51-56)(52-55)(53-55)(54-55)(54-57)(54-58)(56-57)(56-59)(57-59)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MDA-MB-231 | 22 | — | 10.1021/acsabm.4c00689 | 2024 |
| MCF-7 | 33 | — | 10.1021/acsabm.4c00689 | 2024 |
| HeLa | 43 | — | 10.1021/acsabm.4c00689 | 2024 |
| MCF-10A | 92 | — | 10.1021/acsabm.4c00689 | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«The active complexes were found to trigger apoptosis, a vital cellular process crucial for evaluating their potential as anticancer agents utilizing staining assays and flow cytometry analysis.»