Info
| ID | 4312 |
| Metal | Ru |
| Oxidation state | 3 |
| Charge | 0 |
| Donor atoms | {"S": 1, "O": 1, "N": 5} |
| Abbreviation | 11 |
| SMILES | CS(C)=O.Oc1cccc(CNc2nc[nH+]c3nc[nH]c23)c1.[Cl-].[Cl-].[Cl-].[Cl-] |
TUCAN
C14H18N5O2RuS/(1-22)(2-21)(3-19)(4-27)(5-31)(6-31)(7-20)(8-24)(9-26)(10-24)(11-31)(12-32)(13-32)(14-32)(15-33)(16-35)(17-34)(18-39)(19-20)(19-22)(20-30)(21-23)(21-30)(22-23)(23-24)(24-35)(25-28)(25-29)(25-33)(26-34)(26-36)(27-33)(27-37)(28-35)(28-36)(29-34)(29-37)(30-39)(31-40)(32-40)(36-41)(37-41)(38-40)(39-41)(40-41)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| G361 | — | — | 10.1016/j.jinorgbio.2011.04.00... | 2011 |
| K-562 | — | — | 10.1016/j.jinorgbio.2011.04.00... | 2011 |
| HOS | — | — | 10.1016/j.jinorgbio.2011.04.00... | 2011 |
| MCF-7 | — | — | 10.1016/j.jinorgbio.2011.04.00... | 2011 |
🧬 Cell Death Types (1)
Apoptosis
high
«the prepared Ru(III) complexes possess higher pro-apoptotic activity than NAMI-A»