Info
| ID | 4311 |
| Metal | Ru |
| Oxidation state | 3 |
| Charge | 0 |
| Donor atoms | {"S": 1, "O": 1, "N": 5} |
| Abbreviation | 10 |
| SMILES | CS(C)=O.Oc1ccccc1CNc1nc[nH+]c2nc[nH]c12.[Cl-].[Cl-].[Cl-].[Cl-] |
TUCAN
C14H18N5O2RuS/(1-22)(2-19)(3-31)(4-31)(5-27)(6-20)(7-24)(8-24)(9-26)(10-21)(11-31)(12-32)(13-32)(14-32)(15-35)(16-34)(17-33)(18-39)(19-20)(19-22)(20-30)(21-22)(21-23)(23-24)(23-30)(24-33)(25-28)(25-29)(25-35)(26-34)(26-36)(27-35)(27-37)(28-33)(28-36)(29-34)(29-37)(30-39)(31-40)(32-40)(36-41)(37-41)(38-40)(39-41)(40-41)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| G361 | — | — | 10.1016/j.jinorgbio.2011.04.00... | 2011 |
| K-562 | — | — | 10.1016/j.jinorgbio.2011.04.00... | 2011 |
| HOS | — | — | 10.1016/j.jinorgbio.2011.04.00... | 2011 |
| MCF-7 | — | — | 10.1016/j.jinorgbio.2011.04.00... | 2011 |
🧬 Cell Death Types (1)
Apoptosis
high
«the prepared Ru(III) complexes possess higher pro-apoptotic activity than NAMI-A»