Info
| ID | 4309 |
| Metal | Ru |
| Oxidation state | 3 |
| Charge | 0 |
| Donor atoms | {"N": 5, "S": 1, "O": 1} |
| Abbreviation | 8 |
| SMILES | COc1cccc(CNc2nc[nH+]c3nc[nH]c23)c1.CS(C)=O.[Cl-].[Cl-].[Cl-].[Cl-] |
TUCAN
C15H20N5O2RuS/(1-34)(2-23)(3-24)(4-32)(5-32)(6-21)(7-26)(8-34)(9-29)(10-34)(11-28)(12-35)(13-26)(14-22)(15-32)(16-35)(17-35)(18-37)(19-38)(20-36)(21-22)(21-25)(22-24)(23-25)(23-33)(24-33)(25-26)(26-36)(27-30)(27-31)(27-37)(28-37)(28-40)(29-38)(29-39)(30-36)(30-39)(31-38)(31-40)(32-42)(33-42)(34-43)(35-43)(39-44)(40-44)(41-43)(42-44)(43-44)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| G361 | — | — | 10.1016/j.jinorgbio.2011.04.00... | 2011 |
| K-562 | — | — | 10.1016/j.jinorgbio.2011.04.00... | 2011 |
| HOS | — | — | 10.1016/j.jinorgbio.2011.04.00... | 2011 |
| MCF-7 | — | — | 10.1016/j.jinorgbio.2011.04.00... | 2011 |
🧬 Cell Death Types (1)
Apoptosis
high
«the prepared Ru(III) complexes possess higher pro-apoptotic activity than NAMI-A»