Info
| ID | 4308 |
| Metal | Ru |
| Oxidation state | 3 |
| Charge | 0 |
| Donor atoms | {"N": 5, "S": 1, "O": 1} |
| Abbreviation | 7 |
| SMILES | COc1ccccc1CNc1nc[nH+]c2nc[nH]c12.CS(C)=O.[Cl-].[Cl-].[Cl-].[Cl-] |
TUCAN
C15H20N5O2RuS/(1-28)(2-34)(3-23)(4-32)(5-32)(6-21)(7-22)(8-24)(9-29)(10-34)(11-34)(12-35)(13-26)(14-26)(15-32)(16-35)(17-35)(18-37)(19-36)(20-38)(21-23)(21-33)(22-23)(22-24)(24-25)(25-26)(25-33)(26-36)(27-30)(27-31)(27-37)(28-37)(28-39)(29-38)(29-40)(30-36)(30-40)(31-38)(31-39)(32-42)(33-42)(34-43)(35-43)(39-44)(40-44)(41-43)(42-44)(43-44)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| G361 | — | — | 10.1016/j.jinorgbio.2011.04.00... | 2011 |
| K-562 | — | — | 10.1016/j.jinorgbio.2011.04.00... | 2011 |
| HOS | — | — | 10.1016/j.jinorgbio.2011.04.00... | 2011 |
| MCF-7 | — | — | 10.1016/j.jinorgbio.2011.04.00... | 2011 |
🧬 Cell Death Types (1)
Apoptosis
high
«the prepared Ru(III) complexes possess higher pro-apoptotic activity than NAMI-A»