Info
| ID | 4307 |
| Metal | Ru |
| Oxidation state | 3 |
| Charge | 0 |
| Donor atoms | {"S": 1, "O": 1, "N": 5} |
| Abbreviation | 2 |
| SMILES | CS(C)=O.Clc1cccc(CNc2nc[nH+]c3nc[nH]c23)c1.[Cl-].[Cl-].[Cl-].[Cl-] |
TUCAN
C14H17ClN5ORuS/(1-18)(2-19)(3-25)(4-29)(5-29)(6-20)(7-21)(8-23)(9-26)(10-23)(11-29)(12-30)(13-30)(14-30)(15-34)(16-32)(17-33)(18-19)(18-21)(19-31)(20-22)(20-31)(21-22)(22-23)(23-32)(24-27)(24-28)(24-34)(25-34)(25-36)(26-33)(26-35)(27-32)(27-35)(28-33)(28-36)(29-38)(30-38)(31-39)(35-40)(36-40)(37-38)(38-40)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| G361 | — | — | 10.1016/j.jinorgbio.2011.04.00... | 2011 |
| K-562 | — | — | 10.1016/j.jinorgbio.2011.04.00... | 2011 |
| HOS | — | — | 10.1016/j.jinorgbio.2011.04.00... | 2011 |
| MCF-7 | — | — | 10.1016/j.jinorgbio.2011.04.00... | 2011 |
🧬 Cell Death Types (1)
Apoptosis
high
«the prepared Ru(III) complexes possess higher pro-apoptotic activity than NAMI-A»