Info
| ID | 4306 |
| Metal | Ru |
| Oxidation state | 3 |
| Charge | 0 |
| Donor atoms | {"S": 1, "O": 1, "N": 5} |
| Abbreviation | 1 |
| SMILES | CS(C)=O.Clc1ccccc1CNc1nc[nH+]c2nc[nH]c12.[Cl-].[Cl-].[Cl-].[Cl-] |
TUCAN
C14H17ClN5ORuS/(1-18)(2-26)(3-19)(4-29)(5-29)(6-21)(7-23)(8-23)(9-25)(10-20)(11-29)(12-30)(13-30)(14-30)(15-33)(16-34)(17-32)(18-19)(18-21)(19-31)(20-21)(20-22)(22-23)(22-31)(23-32)(24-27)(24-28)(24-34)(25-33)(25-35)(26-34)(26-36)(27-32)(27-35)(28-33)(28-36)(29-38)(30-38)(31-39)(35-40)(36-40)(37-38)(38-40)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| G361 | — | — | 10.1016/j.jinorgbio.2011.04.00... | 2011 |
| K-562 | — | — | 10.1016/j.jinorgbio.2011.04.00... | 2011 |
| HOS | — | — | 10.1016/j.jinorgbio.2011.04.00... | 2011 |
| MCF-7 | — | — | 10.1016/j.jinorgbio.2011.04.00... | 2011 |
🧬 Cell Death Types (1)
Apoptosis
high
«the prepared Ru(III) complexes possess higher pro-apoptotic activity than NAMI-A»