Info
| ID | 4285 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 3} |
| Abbreviation | 1 |
| SMILES | C(=N/c1ccccc1)\c1ncc[nH]1.Cc1ccc(C(C)C)cc1.[Cl-] |
TUCAN
C20H23N3Ru/(1-24)(2-27)(3-24)(4-25)(5-25)(6-24)(7-29)(8-26)(9-26)(10-26)(11-32)(12-33)(13-39)(14-40)(15-30)(16-25)(17-28)(18-38)(19-41)(20-34)(21-31)(22-35)(23-44)(24-38)(25-37)(26-38)(27-29)(27-36)(28-30)(28-36)(29-37)(30-37)(31-32)(31-42)(32-33)(33-34)(34-35)(35-42)(36-38)(39-40)(39-44)(40-45)(41-43)(41-46)(42-46)(43-44)(43-45)(45-47)(46-47)
Measurements (6)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HepG2 | 6 | — | 10.1039/c5dt04781a | 2016 |
| MIA PaCa-2 | 7 | — | 10.1039/c5dt04781a | 2016 |
| MCF-7 | 9 | — | 10.1039/c5dt04781a | 2016 |
| NIH-3T3 | 10 | — | 10.1039/c5dt04781a | 2016 |
| HFF-1 | 10 | — | 10.1039/c5dt04781a | 2016 |
| A549 | 21 | — | 10.1039/c5dt04781a | 2016 |
🧬 Cell Death Types (1)
Apoptosis
high
«The cellular studies show that all the three complexes ... induce cellular death through caspase activation via the mitochondrial pathway.»