Info
| ID | 4222 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 4, "P": 1, "O": 1} |
| Abbreviation | 2b |
| SMILES | C1N2CN3CN1CP(C2)C3.Cc1ccc(C(C)C)cc1.[O-]n1c(=S)ccc2ccccc21 |
TUCAN
C25N4OPRuS/(1-17)(2-16)(3-17)(4-5)(4-16)(5-15)(6-7)(6-25)(7-14)(8-11)(8-13)(9-10)(9-16)(10-15)(11-12)(12-14)(13-18)(14-18)(15-17)(18-29)(19-26)(19-27)(20-26)(20-28)(21-27)(21-28)(22-26)(22-31)(23-27)(23-31)(24-28)(24-31)(25-29)(25-32)(29-30)
Measurements (8)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A2780 | — | — | 10.3390/cancers13102493 | 2021 |
| A549 | — | — | 10.3390/cancers13102493 | 2021 |
| HCT-116 | — | — | 10.3390/cancers13102493 | 2021 |
| OE19 | — | — | 10.3390/cancers13102493 | 2021 |
| HepG2 | — | — | 10.3390/cancers13102493 | 2021 |
| PC-3 | — | — | 10.3390/cancers13102493 | 2021 |
| SK-OV-3 | — | — | 10.3390/cancers13102493 | 2021 |
| SW626 | — | — | 10.3390/cancers13102493 | 2021 |
🧬 Cell Death Types (1)
Apoptosis
medium
«A2780 cells treated with complex 1a only showed partial evidence for apoptotic cell death (8.4% of cell population)»