Info
| ID | 416 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 1} |
| Abbreviation | RANHC-II |
| SMILES | COC(Cn1[c-][n+](C)cc1)c1ccccc1.Cc1ccc(C(C)C)cc1.[I-].[I-] |
TUCAN
C23I2N2ORu/(1-14)(2-14)(3-15)(4-5)(4-15)(5-13)(6-7)(6-15)(7-13)(8-9)(8-16)(9-11)(10-12)(10-16)(11-12)(13-14)(16-23)(17-25)(18-23)(18-24)(19-20)(19-24)(20-25)(21-24)(21-25)(22-26)(23-26)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MDA-MB-231 | — | — | 10.3390/antibiotics12040693 | 2023 |
| MCF-7 | — | — | 10.3390/antibiotics12040693 | 2023 |
| SH-SY5Y | — | — | 10.3390/antibiotics12040693 | 2023 |
| MCF-10A | — | — | 10.3390/antibiotics12040693 | 2023 |
| BALB/3T3 | — | — | 10.3390/antibiotics12040693 | 2023 |
🧬 Cell Death Types (1)
Apoptosis
high
«Thus, using the TUNEL assay we determined whether the Ru-NHC complexes RANHC-V and -VI were able to trigger apoptosis in the MDA-MB-231 cells. ... the breast cancer cells treated with complexes RANHC-...»