Info
| ID | 4113 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"O": 1, "N": 5} |
| Abbreviation | [Ru(bpy)2(quo)][PF6] (5) |
| SMILES | [O-]c1cccc2cccnc12.c1ccc(-c2ccccn2)nc1.c1ccc(-c2ccccn2)nc1 |
TUCAN
C29H22N5ORu/(1-41)(2-23)(3-31)(4-42)(5-25)(6-45)(7-33)(8-24)(9-43)(10-30)(11-35)(12-28)(13-37)(14-27)(15-39)(16-44)(17-29)(18-38)(19-34)(20-36)(21-26)(22-32)(23-24)(23-25)(24-46)(25-41)(26-32)(26-40)(27-37)(27-40)(28-35)(28-42)(29-39)(29-43)(30-31)(30-48)(31-38)(32-33)(33-51)(34-35)(34-49)(36-39)(36-50)(37-45)(38-44)(40-47)(41-52)(42-53)(43-54)(44-56)(45-55)(46-48)(46-52)(47-51)(47-55)(48-56)(49-50)(49-53)(50-54)(51-57)(52-58)(53-58)(54-58)(55-58)(56-58)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | — | — | 10.1021/acs.inorgchem.8b01988 | 2018 |
🧬 Cell Death Types (1)
Apoptosis
high
«An investigation of the mechanism of cell death led to the finding that compounds 1−4 disrupt the mitochondrial transmembrane potential (ΔΨm) in a concentration-dependent fashion, which is an event as...»