Info
| ID | 4111 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"O": 1, "N": 5} |
| Abbreviation | [Ru(bpy)2(hbtz)][PF6] (3) |
| SMILES | [O-]c1ccccc1-c1nc2ccccc2s1.c1ccc(-c2ccccn2)nc1.c1ccc(-c2ccccn2)nc1 |
TUCAN
C33H24N5ORuS/(1-46)(2-47)(3-26)(4-27)(5-29)(6-48)(7-49)(8-34)(9-42)(10-33)(11-31)(12-25)(13-30)(14-37)(15-28)(16-44)(17-35)(18-43)(19-38)(20-36)(21-39)(22-40)(23-41)(24-32)(25-26)(25-30)(26-46)(27-28)(27-47)(28-37)(29-36)(29-48)(30-50)(31-39)(31-49)(32-35)(32-41)(33-34)(33-45)(34-42)(35-43)(36-38)(37-51)(38-52)(39-40)(40-53)(41-54)(42-44)(43-56)(44-55)(45-55)(45-57)(46-58)(47-59)(48-61)(49-62)(50-51)(50-58)(51-59)(52-53)(52-61)(53-62)(54-56)(54-60)(55-63)(56-64)(57-60)(57-64)(58-65)(59-65)(60-65)(61-65)(62-65)(64-65)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | 1.1 | — | 10.1021/acs.inorgchem.8b01988 | 2018 |
🧬 Cell Death Types (1)
Apoptosis
high
«An investigation of the mechanism of cell death led to the finding that compounds 1−4 disrupt the mitochondrial transmembrane potential (ΔΨm) in a concentration-dependent fashion, which is an event as...»