Info
| ID | 4074 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 2 |
| Donor atoms | {"N": 8} |
| Abbreviation | 1 |
| SMILES | CC(O)(CS(=O)(=O)c1ccc(F)cc1)C(=O)Nc1ccc(C#N)c(C(F)(F)F)c1.CC(O)(CS(=O)(=O)c1ccc(F)cc1)C(=O)Nc1ccc(C#N)c(C(F)(F)F)c1.c1ccc(-c2ccccn2)nc1.c1ccc(-c2ccccn2)nc1 |
TUCAN
C56H44F8N8O8RuS2/(1-79)(2-48)(3-47)(4-61)(5-45)(6-97)(7-51)(8-50)(9-56)(10-54)(11-52)(12-45)(13-59)(14-80)(15-63)(16-62)(17-45)(18-97)(19-55)(20-46)(21-57)(22-65)(23-64)(24-49)(25-60)(26-66)(27-46)(28-46)(29-71)(30-68)(31-58)(32-98)(33-67)(34-53)(35-70)(36-69)(37-81)(38-82)(39-72)(40-98)(41-103)(42-104)(43-115)(44-116)(45-89)(46-90)(47-48)(47-79)(48-51)(49-74)(49-85)(50-56)(50-80)(51-83)(52-60)(52-99)(53-75)(53-88)(54-56)(54-84)(55-62)(55-86)(57-65)(57-87)(58-66)(58-99)(59-61)(59-73)(60-93)(61-85)(62-63)(63-81)(64-65)(64-82)(66-93)(67-68)(67-100)(68-94)(69-72)(69-100)(70-71)(70-76)(71-88)(72-94)(73-74)(73-77)(74-95)(75-76)(75-96)(76-78)(77-101)(78-102)(79-105)(80-106)(81-107)(82-108)(83-84)(83-105)(84-106)(85-103)(86-87)(86-107)(87-108)(88-104)(89-91)(89-97)(89-115)(90-92)(90-98)(90-116)(91-103)(91-109)(92-104)(92-110)(93-120)(94-124)(95-117)(95-118)(95-119)(96-121)(96-122)(96-123)(97-126)(98-125)(99-125)(100-126)(105-127)(106-127)(107-127)(108-127)(111-125)(112-125)(113-126)(114-126)(115-127)(116-127)(125-127)(126-127)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| PC-3 | 82 | 49 | 10.1016/j.jinorgbio.2019.03.02... | 2019 |
| PC-3 | 82 | 86 | 10.1016/j.jinorgbio.2019.03.02... | 2019 |
| LNCaP | 86 | 8.9 | 10.1016/j.jinorgbio.2019.03.02... | 2019 |
| LNCaP | 86 | 75 | 10.1016/j.jinorgbio.2019.03.02... | 2019 |
🧬 Cell Death Types (1)
Apoptosis
high
«The potential of these complexes to induce apoptosis in LNCaP cells was performed under light and dark conditions by Hoechst 33342 DNA staining and flow cytometry assay. ... the apoptotic rates induce...»
Source-assisted 2D generator
Builds the drawing from source ligand graphs and explicit donor metadata, then uses Metal2D only for layout. Publication output uses black bonds without arrows or colour highlighting; validated octahedral enantiomers are encoded directly with solid and hashed wedge bonds.
Loading source metadata…
The generated SVG will appear here. The legacy ligand image above stays visible for side-by-side review.