Info
| ID | 4068 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 2} |
| Abbreviation | 4 a |
| SMILES | Cc1ccc(C(C)C)cc1.[Cl-].[c-]1ccccc1-n1cc2ccccc2n1 |
TUCAN
C23ClN2Ru/(1-17)(2-18)(3-18)(4-7)(4-22)(5-6)(5-20)(6-17)(7-9)(8-13)(8-17)(9-14)(10-15)(10-16)(11-16)(11-23)(12-14)(12-22)(13-20)(15-19)(18-20)(19-21)(19-23)(21-25)(22-25)(23-24)(24-25)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MCF-7 | 36 | — | 10.1002/cplu.202000516 | 2020 |
| A549 | 55 | — | 10.1002/cplu.202000516 | 2020 |
| HeLa | — | — | 10.1002/cplu.202000516 | 2020 |
🧬 Cell Death Types (1)
Apoptosis
high
«The new iridium complex 5b with isopropyl substituent in the phenyl ring of 2H-indazole moiety showed good activity against MCF-7 cells and show apoptosis with increased caspase-3/7 activity.»