Info
| ID | 4019 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 2} |
| Abbreviation | 3 |
| SMILES | Cc1ccc(C(C)C)cc1.O=C([N-]c1ccc(F)cc1F)c1ccc2ccccc2n1.[Cl-] |
TUCAN
C26H23F2N2ORu/(1-32)(2-24)(3-33)(4-34)(5-39)(6-24)(7-29)(8-28)(9-27)(10-31)(11-38)(12-37)(13-35)(14-30)(15-36)(16-25)(17-25)(18-25)(19-26)(20-26)(21-43)(22-24)(23-26)(24-40)(25-43)(26-43)(27-29)(27-42)(28-31)(28-48)(29-37)(30-37)(30-46)(31-45)(32-33)(32-40)(33-41)(34-39)(34-41)(35-36)(35-44)(36-42)(38-48)(38-49)(39-40)(41-43)(42-46)(44-47)(44-50)(45-49)(45-51)(46-50)(47-51)(47-52)(48-53)(49-54)(50-55)(51-55)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| ARPE-19 | 3.7 | — | 10.1039/c6dt01464j | 2016 |
| A2780 | 4 | — | 10.1039/c6dt01464j | 2016 |
| HCT-116 | 5.9 | — | 10.1039/c6dt01464j | 2016 |
| A2780cisR | 7.4 | — | 10.1039/c6dt01464j | 2016 |
🧬 Cell Death Types (1)
Apoptosis
high
«Apoptotic analyses revealed a clear correlation between chemosensitivity and levels of apoptosis, whereby the most active compound induces the highest percentage of apoptosis.»