Info
| ID | 3985 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 4} |
| Abbreviation | 6 |
| SMILES | Brc1cnn(-c2nc3ccccc3[nH]2)c1.Cc1ccc(C(C)C)cc1.[I-] |
TUCAN
C20H21BrN4Ru/(1-25)(2-22)(3-26)(4-28)(5-22)(6-22)(7-24)(8-24)(9-35)(10-24)(11-27)(12-32)(13-31)(14-36)(15-29)(16-37)(17-23)(18-23)(19-23)(20-30)(21-42)(22-35)(23-33)(24-35)(25-26)(25-33)(26-34)(27-28)(27-33)(28-34)(29-30)(29-32)(30-31)(31-39)(32-38)(34-35)(36-41)(36-45)(37-41)(37-43)(38-39)(38-42)(39-44)(40-42)(40-43)(40-44)(41-46)(43-45)(44-47)(45-47)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MDA-MB-231 | 9.5 | — | 10.1021/acs.inorgchem.1c02979 | 2021 |
🧬 Cell Death Types (1)
Apoptosis
high
«The representative complexes 3 and 7 demonstrate the capability of arresting the cell cycle in the G2/M phase and induce apoptosis.»