Info
| ID | 3983 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 4} |
| Abbreviation | 4 |
| SMILES | Cc1ccc(C(C)C)cc1.Clc1cnn(-c2nc3ccccc3[nH]2)c1.[I-] |
TUCAN
C20H21ClN4Ru/(1-23)(2-28)(3-29)(4-22)(5-30)(6-23)(7-32)(8-22)(9-37)(10-25)(11-27)(12-36)(13-31)(14-26)(15-23)(16-24)(17-22)(18-35)(19-24)(20-24)(21-42)(22-33)(23-35)(24-35)(25-26)(25-39)(26-27)(27-31)(28-29)(28-33)(29-34)(30-32)(30-34)(31-38)(32-33)(34-35)(36-41)(36-45)(37-41)(37-43)(38-39)(38-42)(39-44)(40-42)(40-43)(40-44)(41-46)(43-45)(44-47)(45-47)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MDA-MB-231 | 9.7 | — | 10.1021/acs.inorgchem.1c02979 | 2021 |
🧬 Cell Death Types (1)
Apoptosis
high
«The representative complexes 3 and 7 demonstrate the capability of arresting the cell cycle in the G2/M phase and induce apoptosis.»