Info
| ID | 3980 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 4} |
| Abbreviation | 1 |
| SMILES | Cc1ccc(C(C)C)cc1.[Cl-].c1ccc2[nH]c(-n3cccn3)nc2c1 |
TUCAN
C20H22N4Ru/(1-28)(2-27)(3-23)(4-29)(5-24)(6-34)(7-23)(8-31)(9-38)(10-32)(11-26)(12-33)(13-39)(14-30)(15-23)(16-24)(17-24)(18-25)(19-37)(20-25)(21-25)(22-43)(23-35)(24-37)(25-37)(26-31)(26-33)(27-28)(27-35)(28-36)(29-34)(29-36)(30-31)(30-41)(32-38)(32-39)(33-40)(34-35)(36-37)(38-44)(39-46)(40-41)(40-45)(41-43)(42-43)(42-44)(42-45)(44-46)(45-47)(46-47)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MDA-MB-231 | — | — | 10.1021/acs.inorgchem.1c02979 | 2021 |
🧬 Cell Death Types (1)
Apoptosis
high
«The representative complexes 3 and 7 demonstrate the capability of arresting the cell cycle in the G2/M phase and induce apoptosis.»