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Complex #3841 — Ru(2) [[Ru(dip)2(CH3bpy-COO)]+]

2D Structure

Structure
⬇ MOL V3000

Info

ID3841
MetalRu
Oxidation state2
Charge1
Donor atoms{"N": 6, "O": 1}
Abbreviation[Ru(dip)2(CH3bpy-COO)]+
SMILESCc1ccnc(-c2cc(C(=O)[O-])ccn2)c1.c1ccc(-c2ccnc3c2ccc2c(-c4ccccc4)ccnc23)cc1.c1ccc(-c2ccnc3c2ccc2c(-c4ccccc4)ccnc23)cc1

TUCAN

C60H41N6O2Ru/(1-43)(2-54)(3-57)(4-47)(5-52)(6-59)(7-53)(8-62)(9-56)(10-63)(11-69)(12-89)(13-48)(14-58)(15-90)(16-65)(17-71)(18-61)(19-44)(20-49)(21-72)(22-67)(23-64)(24-94)(25-46)(26-73)(27-51)(28-66)(29-91)(30-45)(31-68)(32-93)(33-50)(34-70)(35-60)(36-55)(37-42)(38-74)(39-92)(40-42)(41-42)(42-76)(43-47)(43-62)(44-75)(44-89)(45-82)(45-90)(46-76)(46-94)(47-78)(48-49)(48-77)(49-81)(50-84)(50-91)(51-55)(51-83)(52-54)(52-78)(53-57)(53-79)(54-62)(55-88)(56-59)(56-79)(57-69)(58-63)(58-80)(59-69)(60-85)(60-93)(61-65)(61-80)(63-71)(64-86)(64-92)(65-71)(66-67)(66-87)(67-72)(68-70)(68-87)(70-72)(73-86)(73-96)(74-76)(74-97)(75-77)(75-78)(77-95)(79-82)(80-84)(81-82)(81-98)(83-84)(83-99)(85-87)(85-88)(86-101)(88-100)(89-102)(90-103)(91-104)(92-105)(93-106)(94-107)(95-98)(95-102)(96-97)(96-105)(97-107)(98-103)(99-100)(99-104)(100-106)(101-108)(101-109)(102-110)(103-110)(104-110)(105-110)(106-110)(107-110)

Measurements (4)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
A5496— 10.1007/s00775-014-1187-5 2014
MAgEC 10.57.2— 10.1007/s00775-014-1187-5 2014
MLuMEC7.7— 10.1007/s00775-014-1187-5 2014
4T18.7— 10.1007/s00775-014-1187-5 2014

🧬 Cell Death Types (1)

Apoptosis high
«4T1 cells after incubation with ruthenium compounds show marked morphological sign of apoptosis, such as decreasing amount of detached cells, cells rounding and shrinkage... The results suggest that c...»

Source-assisted 2D generator

Builds the drawing from source ligand graphs and explicit donor metadata, then uses Metal2D only for layout. Publication output uses black bonds without arrows or colour highlighting; validated octahedral enantiomers are encoded directly with solid and hashed wedge bonds.

experimental validation surface
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