Info
| ID | 3787 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 7} |
| Abbreviation | RDC-12 |
| SMILES | CC#N.CC#N.Cc1ccnc(-c2cc(C)ccn2)c1.Cc1ccnc(-c2cc(C)ccn2)c1.[c-]1ccccc1-c1ccccn1 |
TUCAN
C39H38N7Ru/(1-58)(2-46)(3-52)(4-39)(5-70)(6-47)(7-39)(8-68)(9-39)(10-51)(11-41)(12-40)(13-40)(14-40)(15-41)(16-54)(17-55)(18-41)(19-69)(20-43)(21-48)(22-43)(23-56)(24-71)(25-43)(26-49)(27-59)(28-42)(29-42)(30-42)(31-50)(32-57)(33-44)(34-72)(35-60)(36-53)(37-44)(38-44)(39-61)(40-66)(41-62)(42-67)(43-64)(44-65)(45-47)(45-63)(46-47)(46-58)(48-61)(48-68)(49-56)(49-75)(50-62)(50-69)(51-56)(51-70)(52-61)(52-73)(53-58)(53-63)(54-62)(54-74)(55-64)(55-76)(57-64)(57-71)(59-65)(59-77)(60-65)(60-72)(63-75)(66-78)(67-79)(68-80)(69-81)(70-82)(71-83)(72-84)(73-74)(73-80)(74-81)(75-82)(76-77)(76-83)(77-84)(80-85)(81-85)(82-85)(83-85)(84-85)
Measurements (7)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A172 | 3 | — | 10.1124/jpet.105.089342 | 2005 |
| HCT-116 | 3 | — | 10.1124/jpet.105.089342 | 2005 |
| HEK293 | 7.9 | — | 10.1124/jpet.105.089342 | 2005 |
| HS683 | 9 | — | 10.1124/jpet.105.089342 | 2005 |
| RDM4 | 10 | — | 10.1124/jpet.105.089342 | 2005 |
| SH-SY5Y | 15 | — | 10.1124/jpet.105.089342 | 2005 |
| Neuro-2a | 15 | — | 10.1124/jpet.105.089342 | 2005 |
Source-assisted 2D generator
Builds the drawing from source ligand graphs and explicit donor metadata, then uses Metal2D only for layout. Publication output uses black bonds without arrows or colour highlighting; validated octahedral enantiomers are encoded directly with solid and hashed wedge bonds.
Loading source metadata…
The generated SVG will appear here. The legacy ligand image above stays visible for side-by-side review.