Info
| ID | 3773 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 1} |
| Abbreviation | 9 |
| SMILES | Cc1ccc(C(C)C)cc1.O=C(CCc1cccnc1)OCC(=O)OCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F.[Cl-].[Cl-] |
TUCAN
C30Cl2F17NO4Ru/(1-14)(2-13)(3-13)(4-7)(4-15)(5-6)(5-16)(6-21)(7-14)(8-9)(8-14)(9-15)(10-11)(10-16)(11-18)(12-20)(12-29)(13-15)(16-17)(17-31)(18-31)(19-22)(19-34)(20-35)(21-32)(21-34)(22-33)(22-35)(23-24)(23-29)(23-37)(23-38)(24-25)(24-39)(24-40)(25-26)(25-41)(25-42)(26-27)(26-43)(26-44)(27-28)(27-45)(27-46)(28-30)(28-47)(28-48)(29-36)(29-49)(30-50)(30-51)(30-52)
Measurements (2)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A2780 | 40 | — | 10.1021/jm5002748 | 2014 |
| HEK293 | 57 | — | 10.1021/jm5002748 | 2014 |
🧬 Cell Death Types (1)
Apoptosis
medium
«As reflected by the number of subdiploid cells (Figure 4 and Table 4), a moderate effect on apoptosis induction was observed at the 50 μM dose.»