Info
| ID | 3770 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 1} |
| Abbreviation | 6 |
| SMILES | Cc1ccc(C(C)C)cc1.O=C(Cc1ccccn1)OCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F.[Cl-].[Cl-] |
TUCAN
C27Cl2F17NO2Ru/(1-15)(2-14)(3-15)(4-17)(4-19)(5-6)(5-13)(6-14)(7-10)(7-11)(8-9)(8-13)(9-14)(10-17)(11-16)(12-18)(12-23)(13-15)(16-28)(17-28)(18-30)(19-29)(19-30)(20-21)(20-26)(20-33)(20-34)(21-22)(21-35)(21-36)(22-24)(22-37)(22-38)(23-26)(23-40)(23-42)(24-25)(24-39)(24-41)(25-27)(25-43)(25-44)(26-31)(26-32)(27-45)(27-46)(27-47)
Measurements (2)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A2780 | 1.8e+02 | — | 10.1021/jm5002748 | 2014 |
| HEK293 | — | — | 10.1021/jm5002748 | 2014 |
🧬 Cell Death Types (1)
Apoptosis
medium
«As reflected by the number of subdiploid cells (Figure 4 and Table 4), a moderate effect on apoptosis induction was observed at the 50 μM dose.»