Info
| ID | 3769 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 1} |
| Abbreviation | 5 |
| SMILES | CC(C)c1cc(C(C)C)cc(C(C)C)c1.O=C(CCc1cccnc1)OCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F.[Cl-].[Cl-] |
TUCAN
C33Cl2F17NO2Ru/(1-16)(2-16)(3-17)(4-17)(5-18)(6-18)(7-15)(7-20)(8-10)(8-19)(9-15)(9-21)(10-25)(11-20)(11-21)(12-13)(12-19)(13-22)(14-24)(14-29)(15-16)(17-20)(18-21)(19-23)(22-34)(23-34)(24-36)(25-35)(25-36)(26-27)(26-32)(26-39)(26-40)(27-28)(27-41)(27-42)(28-30)(28-43)(28-44)(29-32)(29-46)(29-48)(30-31)(30-45)(30-47)(31-33)(31-49)(31-50)(32-37)(32-38)(33-51)(33-52)(33-53)
Measurements (2)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A2780 | 31 | — | 10.1021/jm5002748 | 2014 |
| HEK293 | — | — | 10.1021/jm5002748 | 2014 |
🧬 Cell Death Types (1)
Apoptosis
medium
«As reflected by the number of subdiploid cells (Figure 4 and Table 4), a moderate effect on apoptosis induction was observed at the 50 μM dose.»