Info
| ID | 3768 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 1} |
| Abbreviation | 4 |
| SMILES | Cc1c(C)c(C)c(C)c(C)c1C.O=C(CCc1cccnc1)OCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F.[Cl-].[Cl-] |
TUCAN
C30Cl2F17NO2Ru/(1-12)(2-13)(3-14)(4-15)(5-16)(6-17)(7-8)(7-18)(8-22)(9-10)(9-18)(10-19)(11-21)(11-26)(12-13)(12-14)(13-15)(14-16)(15-17)(16-17)(18-20)(19-31)(20-31)(21-33)(22-32)(22-33)(23-24)(23-29)(23-36)(23-37)(24-25)(24-38)(24-39)(25-27)(25-40)(25-41)(26-29)(26-43)(26-45)(27-28)(27-42)(27-44)(28-30)(28-46)(28-47)(29-34)(29-35)(30-48)(30-49)(30-50)
Measurements (2)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A2780 | 65 | — | 10.1021/jm5002748 | 2014 |
| HEK293 | 86 | — | 10.1021/jm5002748 | 2014 |
🧬 Cell Death Types (1)
Apoptosis
medium
«As reflected by the number of subdiploid cells (Figure 4 and Table 4), a moderate effect on apoptosis induction was observed at the 50 μM dose.»