Info
| ID | 3766 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 1} |
| Abbreviation | 2 |
| SMILES | COC(=O)CCc1cccnc1.Cc1ccc(C(C)C)cc1.[Cl-].[Cl-] |
TUCAN
C19Cl2NO2Ru/(1-13)(2-13)(3-14)(4-7)(4-12)(5-6)(5-15)(6-16)(7-14)(8-11)(8-12)(9-10)(9-15)(10-19)(11-14)(12-13)(15-17)(16-20)(17-20)(18-22)(19-21)(19-22)
Measurements (2)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A2780 | 2e+02 | — | 10.1021/jm5002748 | 2014 |
| HEK293 | — | — | 10.1021/jm5002748 | 2014 |
🧬 Cell Death Types (1)
Apoptosis
medium
«As reflected by the number of subdiploid cells (Figure 4 and Table 4), a moderate effect on apoptosis induction was observed at the 50 μM dose.»