Info
| ID | 371 |
| Metal | Ru |
| Oxidation state | 3 |
| Charge | 0 |
| Donor atoms | {"N": 3, "O": 1} |
| Abbreviation | RuL |
| SMILES | Cc1cc(C)nc(N=Cc2cc([N+](=O)[O-])ccc2Cl)n1.O.[Cl-].[Cl-].[Cl-] |
TUCAN
C13H11ClN4O2Ru/(1-12)(2-19)(3-12)(4-13)(5-12)(6-13)(7-14)(8-17)(9-16)(10-15)(11-13)(12-21)(13-22)(14-15)(14-20)(15-24)(16-21)(16-22)(17-18)(17-20)(18-19)(18-24)(19-28)(20-26)(21-25)(22-27)(23-25)(23-27)(23-28)(24-31)(26-29)(26-30)(27-32)(28-32)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HepG2 | 29 | — | 10.3390/ijerph192013624 | 2022 |
| T47D | 38 | — | 10.3390/ijerph192013624 | 2022 |
| HCT-116 | 40 | — | 10.3390/ijerph192013624 | 2022 |
| MCF-7 | 47 | — | 10.3390/ijerph192013624 | 2022 |
🧬 Cell Death Types (1)
Apoptosis
high
«The complex induced apoptosis and cell cycle arrest in the S phase of HepG2 cells.»