Info
| ID | 3619 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 3} |
| Abbreviation | 7 |
| SMILES | O=C(/N=C(\[N-]c1ccccc1)NCc1ccccc1)c1cccs1.[Cl-].c1ccccc1 |
TUCAN
C25H22N3ORuS/(1-23)(2-24)(3-25)(4-40)(5-29)(6-32)(7-34)(8-26)(9-38)(10-42)(11-31)(12-42)(13-39)(14-27)(15-46)(16-33)(17-28)(18-30)(19-37)(20-36)(21-35)(22-48)(23-24)(23-25)(24-26)(25-27)(26-28)(27-28)(29-32)(29-39)(30-31)(30-37)(31-43)(32-41)(33-40)(33-46)(34-38)(34-41)(35-36)(35-37)(36-43)(38-39)(40-47)(41-42)(42-48)(43-49)(44-48)(44-49)(44-50)(45-47)(45-50)(45-51)(46-52)(47-52)(49-53)(50-53)(52-53)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HepG2 | 59 | — | 10.1021/acs.organomet.8b00702 | 2018 |
| A549 | 1.4e+02 | — | 10.1021/acs.organomet.8b00702 | 2018 |
| Vero | — | — | 10.1021/acs.organomet.8b00702 | 2018 |
🧬 Cell Death Types (1)
Apoptosis
high
«The cell death mechanism of the active complexes 2 and 3 was found to be apoptosis as assessed by flow cytometry and staining methods.»