Info
| ID | 3618 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 3} |
| Abbreviation | 3 |
| SMILES | Cc1ccc(C(C)C)cc1.Cc1ccc([N-]/C(=N\C(=O)c2ccccc2)NCc2ccccc2)cc1.[Cl-] |
TUCAN
C32H34N3ORu/(1-42)(2-52)(3-63)(4-36)(5-45)(6-35)(7-35)(8-47)(9-36)(10-41)(11-48)(12-49)(13-50)(14-44)(15-43)(16-39)(17-40)(18-56)(19-38)(20-53)(21-63)(22-51)(23-38)(24-38)(25-55)(26-36)(27-37)(28-46)(29-37)(30-62)(31-35)(32-54)(33-37)(34-67)(35-58)(36-62)(37-62)(38-61)(39-44)(39-53)(40-43)(40-61)(41-42)(41-52)(42-48)(43-64)(44-49)(45-47)(45-58)(46-54)(46-58)(47-60)(48-57)(49-59)(50-53)(50-59)(51-52)(51-57)(54-60)(55-56)(55-64)(56-61)(57-66)(59-63)(60-62)(63-67)(64-68)(65-67)(65-68)(65-69)(66-69)(66-70)(68-71)(69-71)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HepG2 | 18 | — | 10.1021/acs.organomet.8b00702 | 2018 |
| A549 | 1.3e+02 | — | 10.1021/acs.organomet.8b00702 | 2018 |
| Vero | 1.5e+02 | — | 10.1021/acs.organomet.8b00702 | 2018 |
🧬 Cell Death Types (1)
Apoptosis
high
«The cell death mechanism of the active complexes 2 and 3 was found to be apoptosis as assessed by flow cytometry and staining methods.»