Info
| ID | 3617 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 3} |
| Abbreviation | 2 |
| SMILES | Cc1ccc(C(C)C)cc1.O=C(/N=C(\[N-]c1ccccc1)NCc1ccccc1)c1cccs1.[Cl-] |
TUCAN
C29H30N3ORuS/(1-38)(2-37)(3-34)(4-32)(5-32)(6-32)(7-53)(8-46)(9-36)(10-47)(11-54)(12-44)(13-54)(14-39)(15-48)(16-35)(17-45)(18-40)(19-58)(20-42)(21-43)(22-31)(23-41)(24-33)(25-33)(26-31)(27-31)(28-33)(29-49)(30-60)(31-50)(32-53)(33-53)(34-38)(34-55)(35-39)(35-40)(36-39)(36-52)(37-38)(37-48)(40-44)(41-42)(41-50)(42-51)(43-49)(43-51)(44-52)(45-48)(45-55)(46-47)(46-58)(47-59)(49-50)(51-53)(52-54)(54-60)(55-62)(56-60)(56-61)(56-62)(57-59)(57-61)(57-63)(58-64)(59-64)(61-65)(62-65)(64-65)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HepG2 | 15 | — | 10.1021/acs.organomet.8b00702 | 2018 |
| A549 | 58 | — | 10.1021/acs.organomet.8b00702 | 2018 |
| Vero | 1.4e+02 | — | 10.1021/acs.organomet.8b00702 | 2018 |
🧬 Cell Death Types (1)
Apoptosis
high
«The cell death mechanism of the active complexes 2 and 3 was found to be apoptosis as assessed by flow cytometry and staining methods.»