Info
| ID | 3552 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 6} |
| Abbreviation | [Ru] |
| SMILES | [Cl-].c1ccc(-c2cccc(-c3ccccn3)n2)nc1.c1ccc(-c2nc3c4cccnc4c4ncccc4c3nc2-c2ccccn2)nc1 |
TUCAN
C39H25N9Ru/(1-40)(2-27)(3-34)(4-49)(5-26)(6-50)(7-51)(8-43)(9-44)(10-38)(11-52)(12-36)(13-48)(14-33)(15-30)(16-32)(17-37)(18-35)(19-29)(20-47)(21-31)(22-41)(23-39)(24-28)(25-42)(26-30)(26-35)(27-34)(27-48)(28-38)(28-43)(29-40)(29-41)(30-50)(31-37)(31-51)(32-34)(32-62)(33-36)(33-45)(35-60)(36-47)(37-46)(38-59)(39-42)(39-44)(40-52)(41-64)(42-58)(43-49)(44-57)(45-55)(45-61)(46-54)(46-63)(47-72)(48-69)(49-66)(50-68)(51-65)(52-70)(53-56)(53-62)(53-71)(54-55)(54-65)(55-72)(56-60)(56-67)(57-64)(57-73)(58-59)(58-73)(59-66)(60-68)(61-63)(61-71)(62-69)(63-67)(64-70)(70-74)(71-74)(72-74)(73-74)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MCF-7 | 89 | — | 10.1021/acs.inorgchem.3c00272 | 2023 |
🧬 Cell Death Types (2)
Apoptosis
high
«The Western blot analysis and fluorescence microscopy images suggest that combined apoptosis and autophagy are responsible for cancer cell death.»
Autophagy
high
«The Western blot analysis and fluorescence microscopy images suggest that combined apoptosis and autophagy are responsible for cancer cell death.»