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Complex #3552 — Ru(2) [[Ru]]

2D Structure

Structure
⬇ MOL V3000

Info

ID3552
MetalRu
Oxidation state2
Charge1
Donor atoms{"N": 6}
Abbreviation[Ru]
SMILES[Cl-].c1ccc(-c2cccc(-c3ccccn3)n2)nc1.c1ccc(-c2nc3c4cccnc4c4ncccc4c3nc2-c2ccccn2)nc1

TUCAN

C39H25N9Ru/(1-40)(2-27)(3-34)(4-49)(5-26)(6-50)(7-51)(8-43)(9-44)(10-38)(11-52)(12-36)(13-48)(14-33)(15-30)(16-32)(17-37)(18-35)(19-29)(20-47)(21-31)(22-41)(23-39)(24-28)(25-42)(26-30)(26-35)(27-34)(27-48)(28-38)(28-43)(29-40)(29-41)(30-50)(31-37)(31-51)(32-34)(32-62)(33-36)(33-45)(35-60)(36-47)(37-46)(38-59)(39-42)(39-44)(40-52)(41-64)(42-58)(43-49)(44-57)(45-55)(45-61)(46-54)(46-63)(47-72)(48-69)(49-66)(50-68)(51-65)(52-70)(53-56)(53-62)(53-71)(54-55)(54-65)(55-72)(56-60)(56-67)(57-64)(57-73)(58-59)(58-73)(59-66)(60-68)(61-63)(61-71)(62-69)(63-67)(64-70)(70-74)(71-74)(72-74)(73-74)

Measurements (1)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
MCF-789 10.1021/acs.inorgchem.3c00272 2023

🧬 Cell Death Types (2)

Apoptosis high
«The Western blot analysis and fluorescence microscopy images suggest that combined apoptosis and autophagy are responsible for cancer cell death.»
Autophagy high
«The Western blot analysis and fluorescence microscopy images suggest that combined apoptosis and autophagy are responsible for cancer cell death.»