Info
| ID | 3525 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 2} |
| Abbreviation | C13 |
| SMILES | O=C(NC(=S)Nc1ccc(C(F)(F)F)cc1)c1ccco1.[Cl-].[Cl-].c1ccccc1 |
TUCAN
C19Cl2F3N2O2RuS/(1-4)(1-7)(2-6)(2-14)(3-5)(3-16)(4-8)(5-15)(6-13)(7-11)(8-12)(9-10)(9-14)(10-13)(11-12)(13-18)(14-20)(15-23)(16-17)(16-23)(17-21)(17-22)(18-24)(18-25)(18-26)(19-20)(19-21)(19-27)
Measurements (6)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| IMR-32 | 12 | — | 10.1002/chem.202004954 | 2021 |
| HepG2 | 22 | — | 10.1002/chem.202004954 | 2021 |
| HeLa | 22 | — | 10.1002/chem.202004954 | 2021 |
| A431 | 23 | — | 10.1002/chem.202004954 | 2021 |
| SW40 | 29 | — | 10.1002/chem.202004954 | 2021 |
| Vero | 94 | — | 10.1002/chem.202004954 | 2021 |
🧬 Cell Death Types (1)
Apoptosis
high
«They also promoted cell death by apoptosis and cell cycle arrest.»