Info
| ID | 3523 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 2} |
| Abbreviation | C11 |
| SMILES | CCc1cccc(CC)c1NC(=S)NC(=O)c1ccco1.[Cl-].[Cl-].c1ccccc1 |
TUCAN
C22Cl2N2O2RuS/(1-4)(2-14)(3-5)(3-6)(4-16)(5-9)(6-10)(7-8)(7-19)(8-20)(9-11)(10-11)(12-15)(12-16)(13-15)(13-17)(14-17)(16-18)(17-18)(18-23)(19-26)(20-21)(20-26)(21-24)(21-25)(22-23)(22-24)(22-27)
Measurements (6)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| IMR-32 | 23 | — | 10.1002/chem.202004954 | 2021 |
| HeLa | 30 | — | 10.1002/chem.202004954 | 2021 |
| SW40 | 34 | — | 10.1002/chem.202004954 | 2021 |
| HepG2 | 37 | — | 10.1002/chem.202004954 | 2021 |
| A431 | 38 | — | 10.1002/chem.202004954 | 2021 |
| Vero | 1.2e+02 | — | 10.1002/chem.202004954 | 2021 |
🧬 Cell Death Types (1)
Apoptosis
high
«They also promoted cell death by apoptosis and cell cycle arrest.»