Info
| ID | 3522 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 2} |
| Abbreviation | C10 |
| SMILES | O=C(NC(=S)NCCc1ccccc1)c1ccco1.[Cl-].[Cl-].c1ccccc1 |
TUCAN
C20Cl2N2O2RuS/(1-2)(1-3)(2-12)(3-13)(4-5)(4-10)(5-15)(6-9)(6-15)(7-15)(7-16)(8-11)(8-17)(9-10)(11-18)(12-14)(13-14)(16-21)(17-24)(18-19)(18-24)(19-22)(19-23)(20-21)(20-22)(20-25)
Measurements (6)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| IMR-32 | 22 | — | 10.1002/chem.202004954 | 2021 |
| A431 | 31 | — | 10.1002/chem.202004954 | 2021 |
| HeLa | 32 | — | 10.1002/chem.202004954 | 2021 |
| HepG2 | 35 | — | 10.1002/chem.202004954 | 2021 |
| SW40 | 46 | — | 10.1002/chem.202004954 | 2021 |
| Vero | 1.3e+02 | — | 10.1002/chem.202004954 | 2021 |
🧬 Cell Death Types (1)
Apoptosis
high
«They also promoted cell death by apoptosis and cell cycle arrest.»