Info
| ID | 3521 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 2} |
| Abbreviation | C9 |
| SMILES | O=C(NC(=S)NCc1ccccc1)c1ccco1.[Cl-].[Cl-].c1ccccc1 |
TUCAN
C19Cl2N2O2RuS/(1-2)(1-3)(2-11)(3-12)(4-5)(4-14)(5-9)(6-8)(6-14)(7-10)(7-16)(8-9)(10-17)(11-13)(12-13)(14-15)(15-20)(16-23)(17-18)(17-23)(18-21)(18-22)(19-20)(19-21)(19-24)
Measurements (6)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| IMR-32 | 21 | — | 10.1002/chem.202004954 | 2021 |
| HepG2 | 28 | — | 10.1002/chem.202004954 | 2021 |
| HeLa | 30 | — | 10.1002/chem.202004954 | 2021 |
| A431 | 39 | — | 10.1002/chem.202004954 | 2021 |
| SW40 | 56 | — | 10.1002/chem.202004954 | 2021 |
| Vero | 1.1e+02 | — | 10.1002/chem.202004954 | 2021 |
🧬 Cell Death Types (1)
Apoptosis
high
«They also promoted cell death by apoptosis and cell cycle arrest.»