Info
| ID | 3520 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 2} |
| Abbreviation | C8 |
| SMILES | O=C(NC(=S)Nc1ccccc1)c1ccco1.[Cl-].[Cl-].c1ccccc1 |
TUCAN
C18Cl2N2O2RuS/(1-2)(1-3)(2-11)(3-12)(4-6)(4-9)(5-6)(5-14)(7-10)(7-15)(8-9)(8-14)(10-16)(11-13)(12-13)(14-19)(15-22)(16-17)(16-22)(17-20)(17-21)(18-19)(18-20)(18-23)
Measurements (6)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| IMR-32 | 23 | — | 10.1002/chem.202004954 | 2021 |
| HeLa | 29 | — | 10.1002/chem.202004954 | 2021 |
| A431 | 36 | — | 10.1002/chem.202004954 | 2021 |
| HepG2 | 38 | — | 10.1002/chem.202004954 | 2021 |
| SW40 | 40 | — | 10.1002/chem.202004954 | 2021 |
| Vero | 1.3e+02 | — | 10.1002/chem.202004954 | 2021 |
🧬 Cell Death Types (1)
Apoptosis
high
«They also promoted cell death by apoptosis and cell cycle arrest.»