Info
| ID | 3519 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 2} |
| Abbreviation | C7 |
| SMILES | Cc1ccc(C(C)C)cc1.O=C(NC(=S)Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ccco1.[Cl-].[Cl-] |
TUCAN
C24Cl2F6N2O2RuS/(1-14)(2-13)(3-13)(4-5)(4-15)(5-14)(6-16)(6-17)(7-11)(7-15)(8-9)(8-19)(9-20)(10-16)(10-18)(11-14)(12-17)(12-18)(13-15)(16-22)(17-23)(18-26)(19-28)(20-21)(20-28)(21-25)(21-27)(22-29)(22-30)(22-31)(23-32)(23-33)(23-34)(24-25)(24-26)(24-35)
Measurements (6)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| IMR-32 | 22 | — | 10.1002/chem.202004954 | 2021 |
| HeLa | 39 | — | 10.1002/chem.202004954 | 2021 |
| HepG2 | 40 | — | 10.1002/chem.202004954 | 2021 |
| A431 | 54 | — | 10.1002/chem.202004954 | 2021 |
| SW40 | 55 | — | 10.1002/chem.202004954 | 2021 |
| Vero | 1.3e+02 | — | 10.1002/chem.202004954 | 2021 |
🧬 Cell Death Types (1)
Apoptosis
high
«They also promoted cell death by apoptosis and cell cycle arrest.»